Research
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Our lab specializes in immunoengineering and the molecular engineering of biosensors for live immune cell imaging. Our research goals focus on:
Our lab specializes in immunoengineering and the molecular engineering of biosensors for live immune cell imaging. Our research goals focus on:
1) developing an effective, noninvasive, remotely controllable CAR-T cell-based immunotherapy for solid tumor treatment, as well as ultrasound–controllable gene therapy;
1) developing an effective, noninvasive, remotely controllable CAR-T cell-based immunotherapy for solid tumor treatment, as well as ultrasound–controllable gene therapy;
2) developing tools that illuminate molecular signaling landscapes in live T cells during their engagement with target cells, using genetically encoded biosensors and multiplexed imaging.
2) developing tools that illuminate molecular signaling landscapes in live T cells during their engagement with target cells, using genetically encoded biosensors and multiplexed imaging.
1. Synthetic Biology for Noninvasive Remote Cellular Reprogramming
2. Decoding Immune Cell Dynamics with Multiplexed Biosensor Imaging
Case 1: Talking to Cells
Remote controllable cell therapy
cell_v09_b.mp4Case 2: Illuminating the Darkness
Imaging of T Cell Activation Engaging with Tumor Cells
Case 3: Feasible Fishing the Cellular Ocean
Directed Evolution in Mammalian Cells
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